Medical Devices for Localized Drug Delivery
AssigneeMallinckrodt Inc.
InventorsGary L. Cantrell, David W. Berberich
Life of this patent
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Abstract
In certain embodiments, the invention relates to an implantable medical device that includes a body having an internal cavity. Receptor sites in the internal cavity may be adapted to repeatedly bind to, temporarily hold, and release an active agent. An opening may extend through the body and into the internal cavity to allow the active agent into and out of the internal cavity. This opening may be sized and shaped to prevent blood cells from entering the internal cavity through the opening while allowing the active agent to enter and/or exit the cavity via the opening. A polymeric structure may be located in the internal cavity. This polymeric structure may include artificial receptor site mimics for the active agent.
Claims16
An implantable medical device comprising:
- an elongate member having an internal cavity defined therein and at least one opening extending from the internal cavity to the outside of the elongate member, the at least one opening sized sufficiently for passage of the active agent therethrough;
- and
- a polymeric structure (20) disposed in the internal cavity and having a plurality of receptor site mimics, each receptor site mimic comprising a molecular imprint of at least one active agent.
Dependencies are inferred from the claim text.