Oligomer Conjugates of Lidocaine and Its Derivatives
AssigneeNektar Therapeutics
InventorsJennifer Riggs-Sauthier, Bo-Liang Deng
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Abstract
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer.
Claims30
A compound comprising a lidocaine residue covalently attached via a linkage to a water-soluble, non-peptidic oligomer.
A composition comprising a compound comprising (i) a lidocaine residue covalently attached via a linkage to a water-soluble, non-peptidic oligomer, and (ii) optionally, a pharmaceutically acceptable excipient.
A composition of matter comprising a compound comprising a lidocaine residue covalently attached via a linkage to a water-soluble, non-peptidic oligomer, wherein the compound is present in a dosage form.
A method comprising covalently attaching a water-soluble, non-peptidic oligomer to a lidocaine residue.
A method comprising administering to a subject a compound comprising a lidocaine residue covalently attached via a linkage to a water-soluble, non-peptidic oligomer.
Dependencies are inferred from the claim text.