Devices and methods for in-line sample preparation of materials
AssigneeGeneral Electric Company
InventorsAnping Zhang, Anthony John Murray, Rui Chen, Wei Yuan
Life of this patent
Estimating the term…
Abstract
A microfluidic device for in-line sample preparation of one or more materials. The microfludic device comprises an in-line tangential flow component. The in-line tangential flow component comprises a first channel through which the sample flows; and one or more additional channels. The first channel and the one ore more channels are separated by a membrane; and wherein a differential is present between the first channel and additional channel that is separated by the membrane.
Claims20
A microfluidic device for in-line sample preparation of one or more materials comprising:
- an in-line tangential flow component comprising:
- a first channel through which a sample flows;
- one or more additional channels;
- wherein the first channel and the one or more additional channels are separated by a membrane comprising silicon, silicon nitride or combinations thereof;
- and
- wherein a differential is present between the first channel and the additional channel that is separated by the membrane.
(canceled)
A microfluidic device for in-line desalting one or more materials comprising:
- an in-line tangential flow component comprising:
- a first channel through which a sample flows;
- one or more additional channels;
- wherein the first channel and the one or more additional channels are separated by a membrane comprising silicon, silicon nitride or combinations thereof;
- and
- wherein an ionic differential is present between the first channel and additional channel that is separated by the membrane.
A microfluidic device for in-line concentration one or more materials comprising:
- an in-line tangential flow component comprising:
- a first channel through which a sample flows;
- one or more additional channels;
- wherein the first channel and the one or more additional channels are separated by a membrane comprising silicon, silicon nitride or combinations thereof;
- and
- wherein an electrical differential is present between the first channel and additional channel that is separated by the membrane.
A method for in-line concentration of one or more materials comprising:
- providing a microfluidic device comprising:
- an in-line tangential flow component comprising:
- a first channel through which a sample feed flows;
- one or more additional channels;
- wherein the first channel and the one or more additional channels are separated by a membrane;
- and wherein a differential is present between the first channel and additional channel that is separated by the membrane;
- introducing the sample feed in the first channel and allowing the sample feed to flow in a tangential manner from the first channel to the one or more additional channels through the porous membrane based on the differential.
Dependencies are inferred from the claim text.