US 2010/0300627 A1 · PREPARATIVE SEPARATION/PRECIPITATION SYSTEM

Abstract

Collection containers (17) are heated by head conduction from a container rack (18) with a heater (19) as the heat source. When an eluting solvent is supplied into a trap column (7) by a pump (5), an eluate containing a target compound exiting from the column (7) flows through a preparative separation passage (13) and drips from a solution nozzle (13a), and this solution is separated into fine droplets by a gas stream blowing from a gas ejection nozzle (15a). When a droplet touches an inner wall of the container (17), the volatile solvent immediately vaporizes, leaving the target compound precipitated in solid forms on the inner wall. Thus, the process of vaporizing and drying the eluate to collect the target compound is completed within a short period of time. This process can be performed online and hence is suitable for laborsaving.

Claims12

Dependent claims

A preparative separation/purification system for obtaining a target component in solid forms by vaporizing a solvent in a solution containing the target component obtained by a preparative separation process, which is characterized by comprising:

a) a container for collecting the target component in solid forms;
b) a heating means for heating the container;
c) a solution passage and a liquid supply means for supplying the solution so that the solution is dripped or poured into the container;
and
d) a gas supply means for producing a gas stream so as to scatter the solution dripped or poured from an end of the solution passage into the container,
where vaporization of the solvent in the solution is accelerated by producing the gas steam by the gas supply means so that the gas stream separates the solution into droplets and brings these droplets into contact with an inner wall of the container heated by the heating means, to obtain the target component in dry, solid forms.

3 more elements

Dependencies are inferred from the claim text.

Preparative separation/precipitation system

Life of this patent

Preparative separation/precipitation system

Life of this patent

Abstract

Claims12