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AssigneeAlexza Pharmaceuticals, Inc.
InventorsC.V. Krishnamohan Sharma, Mingzu Lei, Peter D. Noymer, Daniel J. Myers
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A device for vaporizing a composition. The device comprises a thermally conductive substrate having a surface, the surface comprising a thermally conductive surface structure. A dry composition capable of a solid to liquid phase change upon being heated to at least a select temperature is disposed on the surface structure. The surface structure is configured to form liquid droplets of the composition upon heating of the surface structure to at least the select temperature. The liquid droplets have a median diameter less than a median diameter of liquid droplets formed on a planar substrate surface heated to at least the select temperature.
A device for vaporizing a composition comprising:
A drug supply unit, wherein the drug supply unit is configured to heat a drug composition coated on a surface of a thermally conductive substrate to a temperature sufficient to vaporize the drug composition, the drug supply unit comprising a surface structure operatively associated with the surface, the surface structure being configured such that a drug composition vaporized from the surface comprising the surface structure exhibits a purity that is greater than the purity of a drug vaporized from the surface without the surface structure.
An aerosol drug delivery device comprising:
A substrate having a surface for bearing a composition to be vaporized by heating of the substrate, the substrate surface comprising thermally conductive particles of a size less than 100 μm supported in a silicate binder in a manner preventing the formation of droplets of the composition on the substrate surface of a diameter greater than 2000 μm in diameter during vaporization of a layer of the composition applied to the substrate.
A method of making a device for vaporizing a composition, comprising:
Dependencies are inferred from the claim text.