Assay for measuring plasma FGL-2 and methods and uses thereof
AssigneeVeritas Therapeutics Inc.
InventorGary Levy
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Abstract
The disclosure relates to methods for identifying a subject having elevated FGL2 plasma levels, the method comprising the step of assaying a plasma sample from the subject to determine a level of FGL2, wherein a level above control indicates the subject has elevated FGL2 levels. Diagnostic methods, methods of monitoring prognosis and methods of medical treatment relating to viral hepatitis are also provided. The disclosure also provides assays and kits useful in the diagnosis of a viral hepatitis associated with elevated FGL2.
Claims31
A method for identifying a subject having an elevated FGL2 level in plasma, the method comprising the step of assaying a plasma sample from the subject to determine the level of FGL2, wherein a level above control indicates that the subject has elevated FGL2 levels.
An assay useful in the diagnosis of a viral hepatitis comprising the steps of:
- a) providing a plasma sample from a subject;
- b) reacting the sample with an antibody that binds FGL2;
- c) detecting bound FGL2;
- and
- d) comparing the level of FGL2 in the sample with the level of FGL2 in a control subject, wherein a subject having said viral hepatitis is indicated by a greater level of FGL2 in the sample relative to the level of FGL2 in the control subject.
A kit comprising an antibody that binds FGL2 and instructions for the use thereof in determining the level of FGL2 in a plasma sample.
Dependencies are inferred from the claim text.