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US 2010/0297661 A1Published application
Diagnostic Composition and Kit for Renal Cell Carcinoma
AssigneesDCD, Ltd., Genomine, Inc.
InventorsDong Su Kim, Nam Hoon Cho, Hyung Jin Na, Young Deuk Choi, Jae Ho Jang, Hye-Kyung Kim, Mo Yoel Park, Won Man Park, Tae-hoon Kim, Dong Hee Lee, Kyung Mok Park
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Abstract
Disclosed herein are a composition and a kit for diagnosing renal cell carcinoma. The composition and kit employ, as a renal cell carcinoma marker, nicotinamide N-methyltransferase, L-plastin, secretagogin, NM23A, CapG, which is an actin regulatory protein, and/or C4a anaphylatoxin.
Claims10
1-24. (canceled)
A method for diagnosing renal cell carcinoma comprising steps of
- preparing a composition containing a binding molecule binding specifically to one or more renal cell carcinoma markers selected from the group consisting of NNMT, L-plastin, secretagogin, NM23A, CapG and C4aANA;
- contacting the composition with a biological sample to measure expression level of the marker;
- and
- comparing the expression level of the marker with that in normal tissues of the kidney or in biological samples of normal individuals.
1 more element
Dependencies are inferred from the claim text.