Novel diarylphosphine- and dialkylphosphine-containing compounds, processes of preparing same and uses thereof as tridentate ligands

A combinatorial library of tridentate ligands, the library comprising a plurality of compounds having the general Formula I:

• wherein:
• n is an integer from 1 to 4;
• R1-R4 are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, heteroaryl, heteroalicyclic, alkoxy, thioalkoxy, hydroxy, thiol, amine, nitro and cyano;
• R5 is a leaving group capable of being dissociated so as to form a carbanion;
• D1 is an electron donating group of the general Formula IIa:
• Z1Z2Xa Formula IIa;
• and
• D2 is an electron donating group of the general Formula IIb:
• Z3Z4Xb Formula IIb;
• whereas:
• Xa and Xb are each independently an electron donating atom;
• and
• Z1, Z2, Z3 and Z4 are each independently absent or a substituent selected from the group consisting of substituted or non-substituted aryl, substituted or non-substituted alkyl, substituted or non-substituted alkoxy and substituted or non-substituted aryloxy, or, alternatively, at least two of Z1, Z2, R1 and R2 and/or at least two of Z3, Z4, R3 and R4 from together a five- or six-membered heteroalicyclic or heteroaromatic ring,
• at least one of said D1 and D2 having said general Formula IIa or IIb, respectively, is being such that said electron donating atom is phosphorus and either said Z1 and Z2 or said Z3 and Z4 substituents of said phosphorus are each independently a substituted or non-substituted aryl, or, alternatively, at least one of said D1 and D2 having said general Formula IIa or IIb, respectively, is being such that said electron donating atom is phosphorus and at least one of said Z1 and Z2 or said Z3 and Z4 substituents of said phosphorus is a substituted or non-substituted alkyl or a substituted or non-substituted cyclo alkyl,
• said compounds being different from one another in at least one of said electron donating groups D1 and D2 and/or at least one of said n and R1-R5.

A combinatorial library of organometallic complexes, the library comprising a plurality of organometallic complexes having general Formula V:

• wherein:
• n is an integer from 1 to 4;
• R1-R4 are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, heteroaryl, heteroalicyclic, alkoxy, thioalkoxy, hydroxy, thiol, amine, halogen, nitro and cyano;
• M is a transition metal;
• and
• D1 is an electron donating group of the general Formula IIa:
• Z1Z2Xa Formula IIa;
• and
• D2 is an electron donating group of the general Formula IIb:
• Z3Z4Xb Formula IIb;
• whereas:
• Xa and Xb are each independently an electron donating atom;
• and
• Z1, Z2, Z3 and Z4 are each independently absent or a substituent selected from the group consisting of substituted or non-substituted aryl, substituted or non-substituted alkyl, substituted or non-substituted alkoxy and substituted or non-substituted aryloxy, or, alternatively, at least two of Z1, Z2, R1 and R2 and/or at least two of Z3, Z4, R3 and R4 from together a five- or six-membered heteroalicyclic or heteroaromatic ring,
• at least one of said D1 and D2 having said general Formula IIa or IIb, respectively, is being such that said electron donating atom is phosphorus and either said Z1 and Z2 or said Z3 and Z4 substituents of said phosphorus are each independently a substituted or non-substituted aryl, or, alternatively, at least one of said D1 and D2 having said general Formula IIa or IIb, respectively, is being such that said electron donating atom is phosphorus and at least one of said Z1 and Z2 or said Z3 and Z4 substituents of said phosphorus is a substituted or non-substituted alkyl or a substituted or non-substituted cycloalkyl, said complexes being different from one another in at least one of said metal, said electron donating groups D1 and D2 and at least one of said n and R1-R5.

A compound having a general Formula VIII:

• wherein:
• Q is selected from the group consisting of azide, halide, carboxy, and hydroxy;
• and
• at least one of Za and Zb is a substituted or non-substituted alkyl or a substituted or non-substituted cycloalkyl.