Replikin peptides in rapid replication of glioma cells and in influenza epidemics
OwnerSamuel BOGOCH, Elenore S. BOGOCHinventors
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Abstract
Peptides of influenza virus hemagglutinin protein and Plasmodium falciparum malaria antigen, antibodies specific for the peptides, influenza vaccines, malaria vaccines and methods of stimulating the immune response of a subject to produce antibodies to influenza virus or malaria are disclosed. Also disclosed are methods for formulating vaccines for influenza virus.
Claims4
1-12. (canceled)
An antisense nucleic acid molecule complementary to an influenza virus hemagglutinin Replikin mRNA sequence, said Replikin mRNA sequence having from 7 to about 50 amino acids comprising
- (1) at least one lysine residue located six to ten residues from a second lysine residue;
- (2) at least one histidine residue;
- and (3) at least 6% lysine residues.
An antisense nucleic acid molecule complementary to the coding strand of the gene or the mRNA encoding influenza virus hemagglutinin, wherein said antisense nucleic acid molecule is complementary to a nucleotide sequence present in an emerging strain of influenza virus.
15-48. (canceled)
Dependencies are inferred from the claim text.