Cattle Reproductive Disease Vaccines
AssigneePfizer Inc.
InventorsPaul J. Dominowski, Michael John Huether, Mark D. Goodyear
Life of this patent
Estimating the term…
Abstract
The present invention relates to combination vaccines and methods for treating or preventing diseases or disorders in an animal caused by infection by Bovine Viral Diarrhea Virus (BVDV) Types 1 and 2, Bovine Herpes Virus Type-1 (BHV-1), Bovine Respiratory Syncytial Virus (BRSV), Parainfluenza Virus (PI3), Campylobacter fetus, Leptospira canicola, Leptospira grippotyphosa, Leptospira hardj-prajitno, Leptospira icterohaemmorrhagiae, Leptospira hardjo-bovis and Leptospira pomona by administering to the animal an effective amount of a combination vaccine. The combination vaccine can be a whole or partial cell inactivated or modified live preparation.
Claims58
-11. (canceled)
A method of inducing an immune response against Bovine Herpes Virus Type 1 in an animal subject, comprising administering an immunologically effective amount of the composition of claim 1 and a veterinarily-acceptable carrier.
A method of inducing an immune response against Bovine Viral Diarrhea Virus Type-1 in an animal subject, comprising administering an immunologically effective amount of the composition of claim 1 and a veterinary-acceptable carrier.
A method of inducing an immune response against Bovine Viral Diarrhea Virus Type-2 in an animal subject, comprising administering an immunologically effective amount of the composition of claim 1 and a veterinary-acceptable carrier.
A method of inducing an immune response against parainfluenza virus Type 3 (PI3) in an animal subject, comprising administering an immunologically effective amount of the composition of claim 1 and a veterinary-acceptable carrier.
A method of inducing an immune response against Bovine Respiratory Syncytial Virus (BRSV) in an animal subject, comprising administering an immunologically effective amount the composition of claim 1 and a veterinary-acceptable carrier.
A method of inducing an immune response against Campylobacter fetus in an animal subject, comprising administering an immunologically effective amount of the composition of claim 1 and a veterinary-acceptable carrier.
A method of inducing an immune response against an antigen selected from the group consisting of Leptospira canicola, Leptospira grippotyphosa, Leptospira borgpetersenii hardioprajano, Leptospira icterohaemmorrhagia, Leptospira interrogans pomona, Leptospira horgpetersenii hardjo-hovis, Leptospira bratislava, Neospora caninum, Trichomonus fetus, Mycoplasma, bovis, Haemophilus somnus, Mannheimia haemolytica and Pasturella multocida in an animal subject, comprising administering;
- an immunologically effective amount of the composition of claim 1 and a veterinary-acceptable carrier.
-31. (canceled)
A method of preventing abortion caused by Bovine Herpes Virus (BHV-1) in an animal comprising administering to said animal a therapeutically effective amount of a vaccine composition comprising:
- a modified live Bovine Herpes Virus (BHV-1);
- a modified live parainfluenza virus Type 3 (PI3);
- a modified live Bovine Respiratory Syncytial Virus (BRSV);
- a Bovine Viral Diarrhea Virus Type-1 (BVDV-1);
- a Bovine Viral Diarrhea Virus Type-2 (BVDV-2);
- an adjuvant;
- and
- a veterinarily-acceptable carrier.
-38. (canceled)
-42. (canceled)
A method of treating or preventing a disease or disorder in an animal caused by infection with a virus selected from the group consisting of BVDV Type 1 or Type 2, BHV-1, PI3 or BRSV comprising administering to said animal a therapeutically effective amount of the vaccine composition of claim 20.
A method of treating or preventing a disease or disorder in an animal caused by infection with an antigen selected from the group consisting Leptospira canicola, Leptospira grippotyphosa, Leptospira borgpetersenii hardio-prajitno, Leptospira icterohaemmorrhagia, Leptospira interrogans pomona, Leptospira borgpetersenii hardjo-bovis, Leptospira Bratislava, Campylobacter fetus, Neospora caninum, Trichomonus fetus, Mycoplasma, Bovis, Haemophilus somnus, Mannheimia haemolytica and Pasturella multocida, comprising administering to said animal a therapeutically effective amount of the vaccine composition of claim 20.
A method of treating or preventing persistent fetal infection in an animal subject, comprising administering to said animal an effective amount of a vaccine composition comprising:
- a modified live Bovine Herpes Virus (BHV-1);
- a modified live parainfluenza virus Type 3 (PI3);
- a modified live Bovine Respiratory Syncytial. Virus (BRSV);
- a Bovine Viral Diarrhea Virus Type-1 (BVDV-1);
- a Bovine Viral. Diarrhea Virus Type-2 (BVDV-2);
- an adjuvant;
- and
- a veterinarily-acceptable carrier.
-71. (canceled)
-83. (canceled)
Dependencies are inferred from the claim text.