Controlled exotherm of cyanoacrylate formulations
OwnerBinoy K. Bordoloi, Melanie A. Vander Klokinventors
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Abstract
The present invention is directed to curable cyanoacrylate-based formulation containing a multi-functional amine initiator. A dual function amine, particularly Quadrol, provides a highly desirable balance of maximum cure temperature and setting time of cure with the same higher viscosity, non-running cyanoacrylate formulation. The present invention is also directed to systems that utilize the inventive formulations and methods for use of such formulations.
Claims20
An adhesive composition comprising:
- a) one or more polymerizable cyanoacrylate monomers and
- b) a multifunctional compound having at least two amine functional groups and at least one hydroxy moiety,
- wherein each amine functional group has a different pKa value from the pKa value of the other amine functional group.
A system for treating living tissue comprising:
- a) a first reservoir containing one or more polymerizable cyanoacrylate monomers, and
- b) a second reservoir in a non-contacting relationship with the first reservoir containing a polymerization initiator for the one or more polymerizable cyanoacrylate monomers comprising a multifunctional compound having at least two amine functional groups and at least one hydroxy moiety,
- wherein each amine functional group has a different pKa value from the pKa value of the other amine functional group;
- and
- c) an applicator capable of combining the polymerizable cyanoacrylate monomer and the polymerization initiator to form an adhesive composition and then applying the adhesive composition to living tissue.
A system according to claim 17 wherein the polymerized cyanoacrylate monomers are bioabsorbable.
Dependencies are inferred from the claim text.