US 2010/0249383 A1 · Novel Ligand Involved In The Transmigration Of Leukocytes Across the Endothelium and Uses Therefor

Abstract

The present invention provides methods and compositions involved in the inflammatory response, as well as various pathological processes. In particular, the present invention provides novel antibodies directed against novel glycans that are enriched on endothelial cell surfaces. In addition, the present invention provides methods and compositions involved in a previously unrecognized pathway of the inflammatory response and various pathological processes. In addition the present invention provides methods and compositions suitable to mediate the inflammatory response in various settings, as well as methods and compositions for the identification of other inflammatory response mediators.

Claims6

Dependent claims

1-52. (canceled)

Dependencies are inferred from the claim text.

Facts

Application

12/501,926Filed 13 Jul 2009

Priority

28 Dec 2001

Published

30 Sep 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification9 codes

C07H 1/00
Processes for the preparation of sugar derivatives
C07K 16/28
Against material from animals or humans: against receptors, cell surface antigens or cell surface determinants
C07K 16/30
Against receptors, cell surface antigens or cell surface determinants: from tumour cells
C07K 16/3084
Against structure-related tumour-associated moieties: against tumour-associated gangliosides

Novel Ligand Involved In The Transmigration Of Leukocytes Across the Endothelium and Uses Therefor

Life of this patent

Novel Ligand Involved In The Transmigration Of Leukocytes Across the Endothelium and Uses Therefor

Life of this patent

Abstract

Claims6