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US 2010/0249374 A1Published application
Diphenylmethane compound
AssigneeAjinomoto Co., Inc.
InventorDaisuke TAKAHASHI
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Abstract
Compounds having a diphenylmethane skeleton are superior in broad utility and stability, and are useful as a protecting reagent (anchor) of amino acid and/or peptide in the liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide(-CONHR)-type, and in organic synthetic reaction methods (particularly peptide liquid phase synthetic methods), and may be contained in a kit for peptide liquid phase synthesis.
Claims24
A diphenylmethane compound represented by formula (I):
- wherein
- Y is a hydroxyl group or a —NHR group, where R is a hydrogen atom, an alkyl group, or an aralkyl group;
- k and l are each independently an integer of 0 to 5 and k+1 is not 0;
- Each Ra in the number of k and each Rb in the number of 1 are independently an organic group having an aliphatic hydrocarbon group, wherein, in the organic group(s) in the number of (k+1), each having an aliphatic hydrocarbon group, the total carbon number of the aliphatic hydrocarbon groups is not less than 16;
- ring A optionally further has substituent(s) besides Ra;
- and
- ring B optionally further has substituent(s) besides Rb.
4 more elements
Dependencies are inferred from the claim text.