Purification process for lipopeptides
AssigneeCadila Healthcare Limited
InventorsMenka GURNANI, Rajkumar Maurya
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Abstract
The present invention provides simple, cost effective, rapid, and scalable at industrial scale and provide high purity and yield of Echinocandin-type compounds at low cost as compared to prior art. Moreover the process allows for the removal of impurities by using economical salt-adsorbent complex and provide highly purified Echinocandin type compounds which is highly improved in terms of purity and sufficient for further processing to obtain an active pharmaceutical ingredient such as, the antifungals caspogungin, anidulafungin, and micafungin.
Claims17
A process for the purification of Lipopeptide or Echinocandin type compounds comprising the binding of Echinocandin compound on a salt adsorbent, wherein the salt adsorbent is prepared from phosphate and at least one cation.
Dependencies are inferred from the claim text.