Methods and compositions for modulating glutamate dehydrogenase
OwnerThomas Smith, Charles Stanley +1inventors
InventorsThomas Smith, Charles Stanley, Franz Matschinsky
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Abstract
Compositions, compounds, and methods for modulating the activity of glutamate dehydrogenase are disclosed. In addition, compositions, compounds, and methods for regulating insulin secretion and treating hyperinsulism/hyperammonemia and/or diabetes are disclosed.
Claims19
A method for modulating the activity of glutamate dehydrogenase comprising providing to a system in need thereof with an effective amount of a compound selected from the group consisting of EGCG and ECG, including salts, hydrates, solvates, N-oxides, and combinations thereof.
A method for regulating insulin secretion comprising providing to a patient in need thereof with an effective amount of a composition selected from the group consisting of Camellia sinensis extract, EGCG, and ECG, including salts, hydrates, solvates, N-oxides, and combinations thereof.
A method for treating or preventing the effects of HI/HA comprising providing to a patient in need thereof with an effective amount of a compound selected from the group consisting of EGCG and ECG, including salts, hydrates, solvates, N-oxides, and combinations thereof.
Dependencies are inferred from the claim text.