Nitric oxide donor compounds
AssigneeNicox S.A.
InventorsNicoletta Almirante, Silvia Stefanini, Laura Storoni, Fabio Nicoli, Julio Lazaro Padron
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AssigneeNicox S.A.
InventorsNicoletta Almirante, Silvia Stefanini, Laura Storoni, Fabio Nicoli, Julio Lazaro Padron
Estimating the term…
The invention relates to nitric oxide donors of the formula (I) and pharmaceutically acceptable salts or stereoisomers thereof: wherein A and A′ are independently selected from the group consisting of H and —(X)S—Y with the proviso that at least one of A or A′ is not H; wherein s is 0 or 1; X is selected from the group consisting of: —CO—, —COO—, —CONH— and —SO2— or Y is straight or branched C1-C20 alkyl chain, preferably C1-C10 alkyl chain, substituted with one or two —ONO2; or C1-C6 alkylenoxy-C1-C5 alkyl wherein the alkyl group is substituted by one or two —ONO2 groups. The invention also provides novel compositions comprising at least one compound of the invention and at least one therapeutic agent.
A compound of the formula (I) and pharmaceutically acceptable salts or stereoisomers thereof:
(canceled)
Dependencies are inferred from the claim text.