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US 2010/0249178 A1Published application
Compositions and methods for treating middle-of-the-night insomnia
OwnerNikhilesh Singh, Sathasivan Indiran Patherinventors
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Abstract
The present invention provides compositions having a therapeutically effective amount of zolpidem, carbonate buffer, bicarbonate buffer, and a mixture comprising large and fine particles of silicon dioxide. Compositions having a therapeutically effective amount of zolpidem, carbonate buffer, bicarbonate buffer, and sodium stearyl fumarate are also described.
Claims20
A pharmaceutical composition comprising:
- about 0.5 mg to about 4.75 mg of zolpidem;
- a carbonate buffer;
- a bicarbonate buffer;
- and
- sodium stearyl fumarate.
2 more elements
A solid pharmaceutical composition comprising:
- about 0.5 mg to about 4.75 mg of zolpidem;
- a carbonate buffer;
- a bicarbonate buffer;
- and
- a mixture comprising large and fine particles of silicon dioxide.
2 more elements
A solid pharmaceutical composition comprising:
- a therapeutically effective amount of zolpidem;
- a carbonate buffer;
- a bicarbonate buffer;
- a mixture comprising large and fine particles of silicon dioxide;
- and
- sodium stearyl fumarate.
3 more elements
Dependencies are inferred from the claim text.