Imidazo 1, 2-a pyrimidine derivatives for the treatment of diseases such as diabetes

Compounds of the formula I

• in which
• W denotes
• X1, X2, X3,
• X4, X5, X6 each, independently of one another, denote C—R7, N or C-Het,
• Y denotes O, S, N—R7 or N-Het,
• R1, R2, R3, R4,
• R5, R6, R7 each, independently of one another, independently denote H, A, OH, OA, NAA′, HaI, CN, NO2, O(CH2)mCONAA′, NA(CH2)mCONAA′, (CH2)mNAA′, O(CH2)mNAA′, O(CH2)mOA, O(C═O)(CH2)mNAA′, (C═O)O(CH2)mNAA′, NA(C═O)(CH2)mNAA′, (C═O)NA(CH2)mNAA′, CH2O(CH2)mNAA′, CH2OA or COOA,
• A, A′, A″ each, independently of one another, denote H, linear or branched alkyl having 1-10 C atoms which is unsubstituted or mono-, di- or trisubstituted by ═S, ═NR, ═O (carbonyl oxygen), NRR′, OH, CN, CONRR′ and/or NO2, in which one, two or three CH2 groups may be replaced, independently of one another, by O, S, SO, SO2, NR, —OCO—, —NRCONR′—, —NRCO—, —COO—, —CONR—, —C≡C— groups and/or by —CH═CH— groups and/or, in addition, 1-20H atoms may be replaced by F and/or Cl, or cyclic alkyl having 3-7 C atoms which is unsubstituted or mono-, di- or trisubstituted by ═S, ═NR, ═O (carbonyl oxygen), NRR′, OH, CN, CONRR′ and/or NO2, in which one, two or three CH2 groups may be replaced, independently of one another, by O, S, SO, SO2, NR, —OCO—, —NRCONR′—, —NRCO—, —COO—, —CONR—, —C≡C— groups and/or by —CH═CH— groups and/or, in addition, 1-11H atoms may be replaced by F and/or Cl,
• R, R′,
• R″, R′″ each, independently of one another, denote H, linear or branched alkyl having 1-10 C atoms which is unsubstituted or mono-, di- or trisubstituted by ═S, ═NR, ═O (carbonyl oxygen), NH2, OH, CN, CONH2 and/or NO2, in which one, two or three CH2 groups may be replaced, independently of one another, by O, S, SO, SO2, NH, NCH3, —OCO—, —NHCONH—, —NHCO—, —COO—, —CONH—, —NCH3CO—, CONCH3—, —C≡C— groups and/or by —CH═CH— groups and/or, in addition, 1-20H atoms may be replaced by F and/or Cl, or cyclic alkyl having 3-7 C atoms which is unsubstituted or mono-, di- or trisubstituted by ═S, ═NR, ═O (carbonyl oxygen), NH2, OH, CN, CONH2 and/or NO2, in which one, two or three CH2 groups may be replaced, independently of one another, by O, S, SO, SO2, NH, NCH3, —OCO—, —NHCONH—, —NHCO—, —COO—, —CONH—, —NCH3CO—, CONCH3— and/or by —CH═CH— groups and/or, in addition, 1-11H atoms may be replaced by F and/or Cl,
• T denotes Het, COOR, CONRR′, CONRNRR′, CONROR′, O(CH2)mCONRR′, (CH2)mCONRR′, NR(CH2)mCONR′R″, O(CH2)mOCONRR′, (CH2)mOCONRR′, NR(CH2)mOCONR′R″, O(CH2)mNRCONR′R″, (CH2)mNRCONR′R″ or NR(CH2)mNR′CONR″R′″,
• Het denotes a mono- or bicyclic saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms, which may be mono-, di- or trisubstituted by A, HaI, OA, OH, SA, NAA′, SOA, SO2A, NO2, CN, COOA, COOH, CHO, COA, SO3H OCOA, CONAA′, NA′COA, NACONA′A″, NA′SO2A, SO2NAA′, ═S, ═NR1 and/or ═O (carbonyl oxygen),
• HaI denotes F, Cl, Br or I,
• m denotes 1, 2 or 3,
• and pharmaceutically usable salts and stereoisomers thereof, including mixtures thereof in all ratios.