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US 2010/0248993 A1Published application
Method for making a microarray
OwnerAngeliki Tserepi, Evangelos Gogolides +4inventors
InventorsAngeliki Tserepi, Evangelos Gogolides, Sotirios Kakabakos, Panagiota Petrou, Pinelopi Bayiati, Evrimahos Matrozos
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Abstract
This invention provides a method for protein patterning and fabrication of biomolecule microarrays, based on the selective biomolecule adsorption on hydrophilic versus hydrophobic patterns created by selective plasma deposition of fluorocarbon film.
Claims17
1-23. (canceled)
A method for making a biomolecule microarray on a substrate having a patterned surface with a plurality of hydrophobic and hydrophilic areas, the method comprising
- a) providing a substrate with a pattern on its surface;
- b) contacting the patterned surface with a fluorocarbon plasma wherein a hydrophobic material is selectively deposited on selected areas of the surface of the substrate while, at the same time, the rest of the surface of the substrate is etched;
- c) without any further modification other than plasma exposure described in step b above, contacting the said patterned surface exposed to plasma with a biomolecule solution, or with a plurality of biomolecule solutions, to enable adsorption of the biomolecule.
Dependencies are inferred from the claim text.