Method for Selective Labeling and Detection of Target Nucleic Acids Using Immobilized Peptide Nucleic Acid Probes

A method for selective labeling of target nucleic acids on an array having nucleic acid analogue probes immobilized on a support or supports, comprising:

• adding to the array a detectable label and an agent for introducing the label into unlabeled target nucleic acids, after hybridization of the unlabeled target nucleic acids with the nucleic acid analogue probes, wherein the nucleic acid analogue probes are not reactive with the agent, so that only the target nucleic acids hybridized with the nucleic acid analogue probes are selectively labeled.