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US 2010/0248390 A1Published application
Compositions and methods for identifying ligands of odorant receptors
AssigneeDuke University
InventorsHiroaki Matsunami, Joel D. Mainland
Life of this patent
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Abstract
The present invention relates to compositions and methods for identifying odorant-odorant receptor interactions. In particular, the present invention relates to in silico methods for identifying odorant receptor-odorant interactions based on chemical and physical properties of odorant receptors and odorants.
Claims18
A method of identifying an odorant ligand for an odorant receptor, comprising:
- a) comparing three or more amino acid property descriptors of an odorant receptor with three or more physicochemical properties of a plurality of odorants;
- and
- b) identifying one or more odorant receptor for said odorant receptor based on said comparing.
A system for identifying an odorant ligand for an odorant receptor, comprising:
- a computer program and computer software configured for comparing three or more amino acid property descriptors of an odorant receptor with three or more physicochemical properties of a plurality of odorants;
- and identifying one or more odorant receptor for said odorant receptor based on said comparing.
A method of identifying an odorant receptor for an odorant, comprising:
- a) comparing three or more amino acid property descriptors of a plurality of odorant receptors with three or more physicochemical properties of an odorant;
- and
- b) identifying one or more odorants receptors for said odorant based on said comparing.
A system for identifying an odorant receptor for an odorant, comprising:
- a computer program and computer software configured for three or more amino acid property descriptors of a plurality of odorant receptors with three or more physicochemical properties of an odorant;
- and identifying one or more odorants receptors for said odorant based on said comparing.
Dependencies are inferred from the claim text.