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AssigneeUniversity of Utah Research Foundation
InventorsRussell J. Stewart, Betsy J. Endrizzi, Gang Huang, Vladimir Hlady, Samuel Aaron Poff, Jennifer Schumaker-Parry
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Described herein are methods for electrodepositing a variety of different polymers on metal substrates. The polymers are strongly adhered to the substrates. The substrates produced herein can be used in a number of different applications such as, for example, medical devices and biosensors. For example, the biosensors can be composed of one or more electrodes, where the electrodes have the same or different polymers electrochemically deposited on them. Finally, the methods described herein permit the evaluation of the electrodeposition process as well as monitor the ability of biomolecules to bind to the electrodeposited polymers.
A method for applying a polymer to a metal substrate comprising electrochemically depositing a polymer on the surface of the metal substrate, wherein the polymer comprises at least one aromatic group, and wherein the aromatic group comprises one hydroxyl group.
A medical device comprising a metal substrate having at least one surface and a polymer electrochemically deposited on the surface of the metal substrate, wherein the polymer comprises at least one aromatic group, and the aromatic group comprises one hydroxyl group.
A biosensor comprising a metal substrate having at least one surface and a polymer electrochemically deposited on the surface of the metal substrate, wherein the polymer comprises at least one aromatic group, and the aromatic group comprises one hydroxyl group.
A method for producing a biosensor comprising two or more electrodes, wherein the electrodes comprise a metal substrate, the method comprising:
A method for monitoring the electrodeposition of a polymer on the surface of a metal substrate, the method comprising (a) electrochemically depositing a polymer on the surface of the metal substrate, wherein the polymer comprises at least one aromatic group, and wherein the aromatic group comprises one hydroxyl group, and (b) using surface plasmon resonance spectroscopy to monitor the electrodeposition of the polymer during step (a).
A method for monitoring the absorption of a biomolecule by a polymer electrochemically deposited on a metal substrate, the method comprising (a) contacting the electrochemically deposited polymer with the biomolecule, and (b) using surface plasmon resonance spectroscopy to monitor the binding of the biomolecule to the electrochemically deposited polymer.
Dependencies are inferred from the claim text.