Process for the Production of Ambrafuran
AssigneeCsir
InventorsLucia H. Steenkamp, Mihloti Taka
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Abstract
A method for the cyclodehydration of a 1,4- or 1,5-diol includes the step of exposing a 1,4- or a 1,5-diol to an activated zeolite at a temperature of between about 0° C. and about 110° C. for a period of between about 1 and 24 hours. The activated zeolite is prepared from an inactive NaY or CaY type zeolite by ion exchange with an ammonium salt, to produce an ammonium zeolite and exchange of at least part of the ammonia of the ammonium zeolate with a group II A metal.
Claims17
A method for the cyclodehydration of a 1,4- or 1,5-diol, the method including the step of exposing a 1,4- or a 1,5-diol to an activated zeolite at a temperature of between about 0° C. and about 110° C. for a period of between about 1 and 24 hours, the activated zeolite being prepared from an inactive NaY or CaY type zeolite by ion exchange with an ammonium salt, to produce an ammonium zeolite and exchange of at least part of the ammonia of the ammonium zeolate with a group II A metal.
A method of synthesing (−)-ambrafuran, the method including the microbiological conversion of sclareol to ambradiol followed by cyclodehydration to produce ambrafuran.
Dependencies are inferred from the claim text.