Biosensor

A method of forming a biosensor comprising:

• providing a substrate having buried therein an electronic sensing element for sensing electrical variations due to a change in the status of a biomolecule, and a substrate surface located above the buried electronic sensing element;
• covering the substrate surface with a structured top layer having a top surface above the substrate surface;
• forming in or on the structured top layer a sensing electrode, the sensing electrode configured to sense electrical variations in the biomolecule;
• forming in or on the structured top layer at least one channel for immobilizing the biomolecule via suction:
• electrically coupling the sensing electrode to the electronic sensing element,
• adapting the top surface for placing a biomolecule present in a sample solution thereupon;
• and
• forming within the structured top layer at least one channel that is adapted to exert a suction force on the biomolecule.