Back to results
US 2010/0248263 A1Published application
Biomarkers associated with age-related macular degeneration
AssigneeUniversity of Iowa Research Foundation
InventorGregory S. Hagerman
Life of this patent
Estimating the term…
Abstract
The invention relates to proteins associated with age-related macular degeneration (AMD). These proteins, which are present in blood, are expressed in individuals with AMD at either elevated or reduced levels compared to healthy individuals. The invention provides methods for diagnosing AMD. The invention provides methods for assessing the efficacy of treatment of AMD. The invention provides methods for monitoring the progression of AMD.
Claims11
A method of diagnosing age-related macular degeneration (AMD) in an individual, comprising:
- (a) determining levels of at least two AMD-associated protein markers (biomarkers) in a sample from the individual;
- and
- (b) comparing the levels of the at least two biomarkers in the sample to reference levels of the at least two biomarkers characteristic of a control population of individuals without AMD,
- wherein a difference in the levels of the at least two biomarkers between the sample from the individual and the control population indicates that the individual has an increased likelihood of having AMD, and
- wherein the at least two biomarkers are listed in Tables 4B, 5B, 6B or 7.
2 more elements
Dependencies are inferred from the claim text.