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US 2010/0248240 A1Published application
Gene and protein relating to hepatocellular carcinoma and methods of use thereof
AssigneeOncotherapy Science, Inc.
InventorsYusuke Nakamura, Yoichi Furukawa
Life of this patent
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Abstract
The present invention provides a novel human gene ZNFN3A1 whose expression is markedly elevated in a great majority of HCCs compared to corresponding non-cancerous liver tissues. The gene encodes a protein having a zinc finger domain as well as a SET domain and has been found to form a regulatory complex with RNA helicase and RNA polymerase.
Claims2
A method diagnosing cancer, wherein said method comprises the steps of:
- (a) determining a expression level of the ZNFN3A1 gene in biological sample of specimen;
- (b) comparing the expression level of ZNFN3A1 gene with that in normal sample, and
- (c) defining a high expression level of the ZNFN3A1 gene in the sample as having a cancer.
The method of claim 2, wherein the cancer is hepatocellular carcinoma.
Dependencies are inferred from the claim text.