Titanium oxide-organic polymer conjunction suitable for artificial bone

A method for producing a titanium oxide-organic polymer composite material for artificial bone comprising the steps of:

• forming a titania solution by adding a solution consisting of acidic alcohol and water into an alcohol solution of titaniumtetraalkoxide,
• forming titania gel on the surface of a base material by titania solution treatment by dipping into said solution of 0° C. to 50° C. temperature for several seconds to 1 week the base material, the base material being composed of a polymer compound selected from the group consisting of polyolefin, polyester and nylon, and
• modifying a titanium oxide membrane which forms apatite having a similar Ca/P atom ratio to an apatite of mammalian bone in supersaturated aqueous solution or from mammalian body fluid by dipping said base material on the surface of which titania gel is formed into hot water of 50° C. to 95° C. or solution of room temperature to 95° C. to which acid is added.

The method for producing a titanium-oxide organic polymer composite material for artificial bone of claim 1, wherein titaniumtetraalkoxide is tetraisopropyltitanate, alcohol is ethanol and acid is inorganic acid.

The method for producing a titanium-oxide organic polymer composite material for artificial bone of claim 1, wherein polyolefin is low-density polyethylene, polyester is polyethyleneterephthalate and nylon is 6-nylon.

The method for producing a titanium-oxide organic polymer composite material for artificial bone of claim 1, further comprising forming the titania solution by adding a solution consisting of acidic alcohol and water into a solution of titaniumtetraalkoxide and alcohol and maintaining the temperature at 0° C. to 10° C.

A method for producing a composite material for artificial bone comprising the steps of:

• producing a titanium oxide-organic polymer composite material for artificial bone by forming a titania solution by adding a solution consisting of acidic alcohol and water into alcohol solution of titaniumtetraalkoxide,
• forming titania gel on the surface of a base material by titania solution treatment by dipping into said solution of to 0° C. to 10° C. temperature for from several seconds to 1 week to said base material composed of a polymer compound selected from a group consisting of polyolefin, polyester and nylon,
• modifying a titanium oxide membrane which forms apatite having similar Ca/P atom ratio to an apatite of mammalian bone in supersaturated aqueous solution or from mammalian body fluid by dipping said base material on the surface of which titania gel is formed into hot water of 50° C. to 95° C. or solution of room temperature to 95° C. to which acid is added, and forming said apatite by dipping said composite into supersaturated aqueous solution.

The method for producing a composite material for artificial bone of claim 5, wherein titaniumtetraalkoxide is tetraisopropyltitanate, alcohol is ethanol and acid is inorganic acid.

The method for producing a composite material for artificial bone of claim 5, wherein polyolefin is low-density polyethylene, polyester is polyethyleneterephthalate and nylon is 6-nylon.

The method for producing a composite material for artificial bone of claim 5, wherein forming the titania solution further comprises adding a solution consisting of acidic alcohol and water to a solution of titaniumtetraalkoxide and alcohol and maintaining the temperature at 0° C. to 10° C.

The method for producing a titanium oxide-organic polymer composite material for artificial bone of claim 2, wherein polyolefin is low-density polyethylene, polyester is polyethyleneterephthalate and nylon is 6-nylon.

The method for producing a titanium oxide-organic polymer composite material for artificial bone of claim 2, wherein forming the titania solution further comprises adding a solution consisting of acidic alcohol and water to a solution of titaniumtetraalkoxide and alcohol and maintaining the temperature at 0° C. to 10° C.

The method for producing a titanium oxide-organic polymer composite material for artificial bone of claim 3, wherein forming the titania solution further comprises adding a solution consisting of acidic alcohol and water to a solution of titaniumtetraalkoxide and alcohol and maintaining the temperature at 0° C. to 10° C.

The method for producing a composite material for artificial bone of claim 6, wherein polyolefin is low-density polyethylene, polyester is polyethyleneterephthalate and nylon is 6-nylon.

The method for producing a composite material for artificial bone of claim 6, wherein forming the titania solution further comprises adding a solution consisting of acidic alcohol and water to a solution of titaniumtetraalkoxide and alcohol and maintaining the temperature at 0° C. to 10° C.

The method for producing a composite material for artificial bone of claim 7, wherein forming the titania solution further comprises adding a solution consisting of acidic alcohol and water to a solution of titaniumtetraalkoxide and alcohol and maintaining the temperature at 0° C. to 10° C.