Method for producing calcium phosphate complex
AssigneesIwatani Corporation, National Cerebral and Cardiovascular Center
InventorsKunihiko Koike, Masami Nakagawa, Tsutomu Furuzono
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Abstract
A method of the present invention for producing a calcium phosphate complex including a substrate and calcium phosphate bonded to a surface of the substrate, the method includes the steps of: (a) treating the surface of the substrate; and (b) bonding the calcium phosphate onto the surface of the substrate after the step (a), the step (a) being the step of placing the surface of the substrate in contact with ozone water. Therefore, the method of the present invention makes it possible to bond calcium phosphate and the substrate at a high bonding strength and at a high coverage. In addition, the method of the present invention provides an easy method for producing a calcium phosphate complex.
Claims8
A method for producing a calcium phosphate complex including a substrate and calcium phosphate bonded to a surface of the substrate, the method comprising the steps of:
- (a) treating the surface of the substrate;
- and
- (b) bonding the calcium phosphate onto the surface of the substrate after the step (a),
- the step (a) being the step, of placing the surface of the substrate in contact with ozone water,
- the ozone water having an ozone concentration in a range of 1 ppm or more to 50 ppm or less.
A method for producing a calcium phosphate complex including a substrate and calcium phosphate bonded to a surface of the substrate, the method comprising the steps of:
- (a) treating the surface of the substrate;
- and
- (b) bonding the calcium phosphate onto the surface of the substrate after the step (a),
- the step (a) being the step of placing the surface of the substrate in contact with ozone water,
- the ozone water having an ozone concentration in a range of 1 ppm or more to 50 ppm or less
- the surface of the substrate being kept in contact with the ozone water for a time in a range of 5 minutes or more to 30 minutes or less.
A method for producing a calcium phosphate complex including a substrate and calcium phosphate bonded to a surface of the substrate, the method comprising the steps of:
- (a) treating the surface of the substrate;
- and
- (b) bonding the calcium phosphate onto the surface of the substrate after the step (a),
- the step (a) being the step of placing the surface of the substrate in contact with ozone water,
- the ozone water having an ozone concentration in a range of 1 ppm or more to 50 ppm or less,
- the surface of the substrate being placed in contact with the ozone water at a temperature in a range of 20° C. or more to 60° C. or less.
A method for producing a calcium phosphate complex including a substrate and calcium phosphate bonded to a surface of the substrate, the method comprising the steps of:
- (a) treating the surface of the substrate;
- and
- (b) bonding the calcium phosphate onto the surface of the substrate after the step (a),
- the step (a) being the step of placing the surface of the substrate in contact with ozone water,
- the ozone water having an ozone concentration in a range of 1 ppm or more to 50 ppm or less,
- the surface of the substrate being placed in contact with the ozone water at a temperature in a range of 20° C. or more to 60° C. or less,
- the surface of the substrate being kept in contact with the ozone water for a time in a range of 5 minutes or more to 30 minutes or less.
Dependencies are inferred from the claim text.