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US 2010/0247672 A1Published application
Polyurethane/bone compositions and methods
OwnerScott A. Guelcher, Jerald Dumasinventors
Life of this patent
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Abstract
A flowable, injectable composite that comprises mineralized allograft bone; and at least one degradable polyurethane that has a quasi-prepolymer and a resin mix, the resin mix having a polyester polyol and a catalyst; wherein the composite has a compression strength of greater than about 10 MPa and a modulus of greater than about 1 GPa.
Claims25
A bone composite material comprising lysine diisocyanate (LDI), polycaprolactone, and mineralized bone powder (MBP).
A composite comprising:
- mineralized allograft bone;
- and
- at least one degradable polyurethane that has a quasi-prepolymer and a resin mix, the resin mix having a polyester polyol and a catalyst;
- wherein the composite has a compression strength of greater than about 10 MPa and a modulus of greater than about 1 GPa.
1 more element
A method of treating a wound, comprising:
- providing mixture of mineralized allograft bone;
- and
- at least one degradable polyurethane that has a quasi-prepolymer and a resin mix, the resin mix having a polyester polyol and a catalyst;
- injecting the mixture into a wound site.
1 more element
A method of treating a wound, comprising:
- providing mixture of mineralized allograft bone;
- and
- at least one degradable polyurethane that has a quasi-prepolymer and a resin mix, the resin mix having a polyester polyol and a catalyst;
- compression molding the mixture;
- and
- contacting the molding to the wound site.
3 more elements
A method for preparing biodegradable polyurethanes comprising:
- contacting a flowable quasi-prepolymer comprising free aliphatic polyisocyanate compounds with a polyester polyol hardener having a functionality of at least two and mineralized bone powder to form a reactive liquid mixture.
(canceled)
Dependencies are inferred from the claim text.