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US 2010/0247658 A1Published application
Organic compounds
OwnerGerhard Muhrer, Norbert Rasenack +1inventors
InventorsGerhard Muhrer, Norbert Rasenack, Michael Juhnke
Life of this patent
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Abstract
A process for reducing the tendency of a drug substance to aggregate and/or agglomerate during storage. The process involves micronising the drug substance to give a mean particle size of less than about 10 μm, and exposing the micronised drug substance to a dry environment at an elevated temperature between 40° C. and 120° C. for at least six hours.
Claims10
A process for reducing the tendency of a drug substance to aggregate and/or agglomerate during storage, the process comprising the steps of:
- (a) micronising the drug substance to give a mean particle size of less than about 10 μm;
- and
- (b) exposing the micronised drug substance to a dry environment at an elevated temperature between 40° C. and 120° C. for at least six hours.
(canceled)
Dependencies are inferred from the claim text.