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US 2010/0247649 A1Published application
Pharmaceutical formulations comprising telmisartan and hydrochlorothiazide
AssigneeDr. Reddy's Laboratories, Inc.
InventorsUma Devi Palaparthi, Ashutosh Rout, Maheswara Reddy Arumalla
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Abstract
Pharmaceutical tablets comprising a first layer formulated for immediate release of telmisartan from a dissolving matrix and a second layer formulated for immediate release of hydrochlorothiazide from a dissolving matrix, methods for producing tablets and methods of use for treating hypertension.
Claims13
A pharmaceutical formulation comprising a first portion containing telmisartan in a dissolving matrix and a second portion containing hydrochlorothiazide in a dissolving matrix.
A process for preparing a pharmaceutical bi-layer tablet comprising:
- a) granulating a solid composition comprising a diluent with a solution comprising telmisartan, to provide a first tablet layer composition;
- b) combining hydrochlorothiazide with at least one solid pharmaceutical excipient to provide a second tablet layer composition;
- and
- c) compressing a first tablet layer composition and a second tablet layer composition into a bi-layer tablet.
1 more element
Dependencies are inferred from the claim text.