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US 2010/0247648 A1Published application
Antimicrobial compounds
AssigneeNeobiotics AB
InventorsAnders Grubb, Aftab Jasir, Claes Schalén, Franciszek Kasprzykowski, Regina Kasprzykowska
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Abstract
The invention relates to compositions comprising a compound based on the general formula (I) R1-Arg-R2—NH—CH(R3)—CH2—NH—R4 (I) The composition may be used to eliminate and/or reduce microorganisms such as bacteria, viruses, fungi and protozoa.
Claims8
A method for treating viral, fungal, or a mixture of viral and bacterial infection or disease, the method comprising administering an effective amount of a medicament comprising a compound having the formula (I)
- R1-Arg-R2—NH—CH(R3)—CH2—NH—R4
- wherein
- R1 is benzyloxycarbonyl or 3-phenylpropionyl,
- and
- R2 is an amino acid residue selected from the group consisting of Val, Ile, Leu and Phe,
- and
- R3 is selected from the group consisting of isopropyl, isobutyl, sec.butyl, benzyl, 4-hydroxybenzyl and phenyl
- and
- R4 is an acyl residue comprising a phenyl ring.
6 more elements
Dependencies are inferred from the claim text.