Sustained release tablets with hydromorphone
AssigneeAcino Pharma AG
InventorsMarc Zingraff, Markus Reher
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Abstract
The invention relates to a tablet having a tablet core comprising a plurality of active ingredient-containing pellets and one or more pharmaceutically tolerated excipients and at least one coating applied to the tablet core, the active ingredient-containing pellets containing hydromorphone or a salt or a solvate thereof as active ingredient and having the following structure: a) an inert core, b) an active ingredient layer applied to the inert core, c) a layer applied to the active ingredient layer and retarding the release of the active ingredient and d) a further active ingredient layer on the layer retarding the release of the active ingredient.
Claims10
A tablet comprised of a tablet core having at least one coating applied thereto, said tablet core comprising a plurality of active ingredient-containing pellets and one or more pharmaceutically tolerated excipients, the active ingredient-containing pellets containing hydromorphone or a salt or a solvate thereof as active ingredient and further comprising the following structure:
- a) an inert core,
- b) an active ingredient layer applied to the inert core,
- c) a layer applied to the active ingredient layer and retarding the release of the active ingredient and
- d) a further active ingredient layer on the layer retarding the release of the active ingredient.
An active ingredient-containing pellet comprising the active ingredient hydromorphone and having following structure:
- a) an inert core,
- b) an active ingredient layer applied to the inert core,
- c) a layer applied to the active ingredient layer and retarding the release of the active ingredient and
- d) a further active ingredient layer on the layer retarding the release of the active ingredient.
Dependencies are inferred from the claim text.