Adhesive compositions for the treatment of xerostomia
AssigneeAxiomedic Ltd.
InventorsAbraham J. Domb, Benny Brama, Boaz Mizrahi
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AssigneeAxiomedic Ltd.
InventorsAbraham J. Domb, Benny Brama, Boaz Mizrahi
Estimating the term…
Compositions for the treatment of xerostomia, and methods of making and using thereof are disclosed herein. The compositions are typically in the form of a film or tablet, such as a double layer sticker tablet. The compositions adhere to a buccal surface or mucosal surface in the oral cavity for at least 15 minutes, preferably for at least 30 minutes. The compositions themselves are able to increase the levels of saliva in the mouth without the need for active agents, such sialogogic agents. The compositions optionally contain a non-lipid lubricant, a flavoring agent, and/or a buffering agent. The composition is generally effective at treating or ameliorating the effects of xerostomia for a time period ranging from at least 30 minutes up to eight hours following administration to the buccal or oral mucosa.
A bioadhesive sticker tablet for treating or ameliorating the effects of xerostomia in a patient comprising a pharmaceutically acceptable bioadhesive carrier,
A method for treating or ameliorating the effects of xerostomia in a patient, comprising:
Dependencies are inferred from the claim text.