hUTC AS THERAPY FOR ALZHEIMER'S DISEASE
AssigneeEthicon, Inc.
InventorsANTHONY J. KIHM, ANNA GOSIEWSKA
Life of this patent
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Abstract
Methods for treating Alzheimer's disease, or the symptoms of Alzheimer's disease, are provided. Some embodiments are to methods for treatment comprising administering cells obtained from human umbilical cord tissue, or administering pharmaceutical compositions comprising such cells or prepared from such cells, such as cell derivatives. Some embodiments are to methods for treatment comprising hUTC. Pharmaceutical compositions for use in the inventive methods, as well as kits for practicing the methods are also provided.
Claims21
A method of treating a subject diagnosed with Alzheimer's disease, or having symptoms of Alzheimer's disease, said method comprising administering to the subject a composition comprising a population of isolated human umbilical cord-derived cells such that Alzheimer's disease is treated, wherein the isolated human umbilical cord-derived cells are obtained from human umbilical cord tissue substantially free of blood, wherein the isolated cells self-renew and expand in culture and do not express CD117.
A method of treating a subject diagnosed with Alzheimer's disease, or having symptoms of Alzheimer's disease, said method comprising administering to the subject a composition comprising isolated human umbilical cord-derived cell derivatives, wherein the cell derivatives are obtained from isolated human umbilical cord-derived cells, wherein the isolated human umbilical cord-derived cells are obtained from human umbilical cord tissue substantially free of blood, wherein the isolated cells self-renew and expand in culture and do not express CD117.
A composition used for treating Alzheimer's disease or the symptoms of Alzheimer's disease, said composition comprising a population of human umbilical cord-derived cells, wherein the isolated human umbilical cord-derived cells are obtained from human umbilical cord tissue substantially free of blood, wherein the isolated cells self-renew and expand in culture and do not express CD117.
A composition used for treating Alzheimer's disease or the symptoms of Alzheimer's disease, said composition comprising human umbilical cord-derived cell derivatives, wherein the cell derivatives are obtained from isolated human umbilical cord-derived cells, wherein the isolated human umbilical cord-derived cells are obtained from human umbilical cord tissue substantially free of blood, wherein the isolated cells self-renew and expand in culture and do not express CD117.
A kit used for treating Alzheimer's disease or the symptoms of Alzheimer's disease, said kit comprising a population of postpartum derived cells and a pharmaceutically acceptable carrier and/or diluent, wherein the isolated human umbilical cord-derived cells are obtained from human umbilical cord tissue substantially free of blood, wherein the isolated cells self-renew and expand in culture and do not express CD117.
A kit used for treating Alzheimer's disease or the symptoms of Alzheimer's disease, said kit comprising a postpartum derived cell derivatives and a pharmaceutically acceptable carrier and/or diluent, wherein the cell derivatives are obtained from isolated human umbilical cord-derived cells, wherein the isolated human umbilical cord-derived cells are obtained from human umbilical cord tissue substantially free of blood, wherein the isolated cells self-renew and expand in culture and do not express CD117.
Dependencies are inferred from the claim text.