Beta-glucuronidase inhibitor
AssigneeKao Corporation
InventorsIchiro Mori, Shunichi Akiba
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Abstract
Provided are a novel β-glucuronidase inhibitor including a compound selected from a macrocyclic ketone, a ketone, a macrocyclic lactone, a macrocyclic oxalactone, an ester, an aldehyde, an alcohol, and a terpene of specific kinds, and an environmental hygiene product and a sanitary product each containing the β-glucuronidase inhibitor. Also provided are a composition for suppressing the generation of urine odor and a method of suppressing the generation of urine odor each using a β-glucuronidase inhibitor.
Claims13
A β-glucuronidase inhibitor, comprising a macrocyclic ketone represented by the formula (1):
- wherein n1 represents an integer of 9 to 13;
- m1 represents an integer of 0 to 2;
- and a dashed line portion may comprise one double bond.
A β-glucuronidase inhibitor, comprising a ketone selected from cyclopentadecanone, 3-methylcyclopentadecanone, 3-methyl-4(5)-cyclopentadecen-1-one, 4-cyclopentadecen-1-one, 5-cyclohexadecen-1-one, 8-cyclohexadecen-1-one, 9-cycloheptadecen-1-one, 2-pentylcyclopentenone, α-damascone, β-damascone, cis-jasmone, 2-heptylcyclopentanone, α-ionone, β-ionone, α-methylionone, γ-methylionone, 7-methyl-3,4-dihydro-(2H)-1,5-benzodioxepin-3-one, nootkatone, and 1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-acetonaphthone.
A β-glucuronidase inhibitor, comprising a macrocyclic lactone represented by the formula (2):
- wherein n2 represents an integer of 9 to 13;
- m2 represents an integer of 0 to 3;
- and a dashed line portion comprises one double bond;
- provided that n2+m2=9 to 14.
A β-glucuronidase inhibitor, comprising a macrocyclic oxalactone represented by the formula (3):
- wherein R represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms;
- p represents an integer of 6 to 11;
- and q represents an integer of 2 to 6;
- provided that p+q=10 to 14.
A β-glucuronidase inhibitor, comprising an ester selected from 4(5)-cyclopentadecenolide, 7-cyclohexadecenolide, 10-oxa-16-hexadecanolide, 11-oxa-16-hexadecanolide, citronellyl acetate, linalyl acetate, terpinyl acetate, cinnamyl acetate, cis-3-hexenyl benzoate and methyl-2-nonynoate.
A β-glucuronidase inhibitor, comprising an aldehyde selected from anisaldehyde, cinnamic aldehyde, cuminaldehyde, cyclamen aldehyde, ethylvanillin, 2-methyl-3-(3,4-methylenedioxyphenyl)-propanal, 2-methyl-3-(4-tert-butylphenyl)-propanal, phenylacetaldehyde, 3-phenylpropanal, vanillin, 4-(tricyclo[5.2.1.02,6]decylidene-8)butenal, dimethyltetrahydrobenzaldehyde, 4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxyaldehyde, 4-(4-methyl-3-pentenyl)-3-cyclohexene-1-carboxyaldehyde, 2,6-nonadienal, 2-methylundecanal, hydroxycitronellal and citral.
A β-glucuronidase inhibitor, comprising an alcohol selected from citronellol, geraniol, nerol, linalool, linalool oxide, terpineol, cinnamic alcohol, eugenol, 3-methyl-5-phenyl-1-pentanol and vetiverol.
A β-glucuronidase inhibitor, comprising an ether selected from estragole, 6,6,9α-trimethyl-3α-ethyldodecahydronaphtho[2,1-b]furan, p-cresyl methyl ether, phenylethyl isoamyl ether, 1-methoxycyclododecane, 1-methyl-1-methoxycyclododecane and 4,8,12-trimethyl-13-oxabicyclo-[10.1.0]trideca-4,8-diene.
A β-glucuronidase inhibitor, comprising a terpene selected from α-phellandrene and citronellyl nitrile.
A composition for suppressing generation of urine odor, comprising a β-glucuronidase inhibitor.
A method of suppressing generation of urine odor, comprising:
- applying a β-glucuronidase inhibitor to an object before urine is deposited to the object or before urine is dried after having been deposited to the object.
Dependencies are inferred from the claim text.