Systems and methods for identifying suspicious anomalies using information from a plurality of images of an anatomical colon under study
AssigneeiCAD, Inc.
InventorsSenthil Periaswamy, Michael J. Collins, Ryan McGinnis, Robert L. Van Uitert
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Abstract
Systems, computer-readable media, and methods are presented that identify suspicious anomalies in a colon with higher sensitivity and at a lower false positive rate. A plurality of images of an anatomical colon is acquired. Candidate suspicious anomalies are identified in each image. The candidate suspicious anomalies across images are then compared using registration and matching. Features of candidate suspicious anomalies across images may be jointly evaluated to perform classification.
Claims81
In a computer system comprising at least one processor, at least one storage means and at least one input device, a method of identifying suspicious anomalies in an anatomical colon under study, comprising:
- a. by means of at least one input device, acquiring a plurality of images of the anatomical colon;
- b. by means of at least one processor, registering at least a portion of a first acquired anatomical colon image with respect to at least a portion of a second acquired anatomical colon image;
- c. by means of at least one processor, for said first and second acquired anatomical colon images, identifying at least one candidate suspicious anomaly in said acquired anatomical colon image;
- d. by means of at least one processor, for at least one said candidate suspicious anomaly in the registered first acquired anatomical colon image, determining that at least one candidate suspicious anomaly in the registered second acquired anatomical colon image corresponds to said candidate suspicious anomaly in the registered first acquired anatomical colon image, whereby the corresponding suspicious anomalies constitute a matched set;
- e. by means of at least one processor, classifying at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies as belonging to a true positive class;
- and
- f. by means of at least one storage means, storing information with respect to at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies classified as belonging to a true positive class.
A computer-readable medium having computer-readable instructions stored thereon which, as a result of being executed in a computer system having at least one processor, at least one storage means and at least one input device, instructs the computer system to perform a method of identifying suspicious anomalies in an anatomical colon under study, comprising:
- a. by means of at least one input device, acquiring a plurality of images of the anatomical colon;
- b. by means of at least one processor, registering at least a portion of a first acquired anatomical colon image with respect to at least a portion of a second acquired anatomical colon image;
- c. by means of at least one processor, for said first and second acquired anatomical colon images, identifying at least one candidate suspicious anomaly in said acquired anatomical colon image;
- d. by means of at least one processor, for at least one said candidate suspicious anomaly in the registered first acquired anatomical colon image, determining that at least one candidate suspicious anomaly in the registered second acquired anatomical colon image corresponds to said candidate suspicious anomaly in the registered first acquired anatomical colon image, whereby the corresponding suspicious anomalies constitute a matched set;
- e. by means of at least one processor, classifying at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies as belonging to a true positive class;
- and
- f. by means of at least one storage means, storing information with respect to at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies classified as belonging to a true positive class.
A system for identifying suspicious anomalies in an anatomical colon under study, comprising a computer system with at least one processor, at least one storage means and at least one input device, so configured that the system is operable to:
- a. by means of at least one input device, acquire a plurality of images of the anatomical colon;
- b. by means of at least one processor, register at least a portion of a first acquired anatomical colon image with respect to at least a portion of a second acquired anatomical colon image;
- c. by means of at least one processor, for said first and second acquired anatomical colon images, identify at least one candidate suspicious anomaly in said acquired anatomical colon image;
- d. by means of at least one processor, for at least one said candidate suspicious anomaly in the registered first acquired anatomical colon image, determine that at least one candidate suspicious anomaly in the registered second acquired anatomical colon image corresponds to said candidate suspicious anomaly in the registered first acquired anatomical colon image, whereby the corresponding suspicious anomalies constitute a matched set;
- e. by means of at least one processor, classify at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies as belonging to a true positive class;
- and
- f. by means of at least one storage means, store information with respect to at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies classified as belonging to a true positive class.
In a computer system comprising at least one processor, at least one storage means and at least one input device, a method of identifying suspicious anomalies in an anatomical colon under study, comprising:
- a. by means of at least one input device, acquiring a plurality of images of the anatomical colon;
- b. by means of at least one processor, registering at least a portion of a first acquired anatomical colon image with respect to at least a portion of at least two additional acquired anatomical colon images;
- c. by means of at least one processor, for said first and at least one additional acquired anatomical colon images, identifying at least one candidate suspicious anomaly in said acquired anatomical colon image;
- d. by means of at least one processor, for at least one said candidate suspicious anomaly in the registered first acquired anatomical colon image, determining that at least one candidate suspicious anomaly in at least one of the registered additional acquired anatomical colon images corresponds to said candidate suspicious anomaly in the registered first acquired anatomical colon image, whereby the corresponding suspicious anomalies constitute a matched set;
- e. by means of at least one processor, classifying at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies as belonging to a true positive class;
- and
- f. by means of at least one storage means, storing information with respect to at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies classified as belonging to a true positive class.
A computer-readable medium having computer-readable instructions stored thereon which, as a result of being executed in a computer system having at least one processor, at least one storage means and at least one input device, instructs the computer system to perform a method of identifying suspicious anomalies in an anatomical colon under study, comprising:
- a. by means of at least one input device, acquiring a plurality of images of the anatomical colon;
- b. by means of at least one processor, registering at least a portion of a first acquired anatomical colon image with respect to at least a portion of at least two additional acquired anatomical colon images;
- c. by means of at least one processor, for said first and at least one additional acquired anatomical colon images, identifying at least one candidate suspicious anomaly in said acquired anatomical colon image;
- d. by means of at least one processor, for at least one said candidate suspicious anomaly in the registered first acquired anatomical colon image, determining that at least one candidate suspicious anomaly in at least one of the registered additional acquired anatomical colon images corresponds to said candidate suspicious anomaly in the registered first acquired anatomical colon image, whereby the corresponding suspicious anomalies constitute a matched set;
- e. by means of at least one processor, classifying at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies as belonging to a true positive class;
- and
- f. by means of at least one storage means, storing information with respect to at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies classified as belonging to a true positive class.
A system for identifying suspicious anomalies in an anatomical colon under study, comprising a computer system with at least one processor, at least one storage means and at least one input device, so configured that the system is operable to:
- a. by means of at least one input device, acquire a plurality of images of the anatomical colon;
- b. by means of at least one processor, register at least a portion of a first acquired anatomical colon image with respect to at least a portion of at least two additional acquired anatomical colon images;
- c. by means of at least one processor, for said first and at least one additional acquired anatomical colon images, identify at least one candidate suspicious anomaly in said acquired anatomical colon image;
- d. by means of at least one processor, for at least one said candidate suspicious anomaly in the registered first acquired anatomical colon image, determine that at least one candidate suspicious anomaly in at least one of the registered additional acquired anatomical colon images corresponds to said candidate suspicious anomaly in the registered first acquired anatomical colon image, whereby the corresponding suspicious anomalies constitute a matched set;
- e. by means of at least one processor, classify at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies as belonging to a true positive class;
- and
- f. by means of at least one storage means, store information with respect to at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies classified as belonging to a true positive class.
In a computer system comprising at least one processor, at least one input device and at least one output device, a method of presenting suspicious anomalies in an anatomical colon under study, comprising:
- a. by means of at least one input device, acquiring a plurality of images of the anatomical colon;
- b. by means of at least one processor, processing the plurality of images to identify at least one suspicious anomaly appearing in at least two images of the anatomical colon;
- c. by means of at least one processor, based on locations in which the at least one suspicious anomaly appears in the at least two images, creating a display image using a portion of the at least two images, wherein the at least one suspicious anomaly is specially depicted in the display image;
- and
- d. by means of at least one output device, outputting to a user the display image.
A computer-readable medium having computer-readable instructions stored thereon which, as a result of being executed in a computer system having at least one processor, at least one storage means and at least one input device, instructs the computer system to perform a method of identifying suspicious anomalies in an anatomical colon under study, comprising:
- a. by means of at least one input device, acquiring a plurality of images of the anatomical colon;
- b. by means of at least one processor, processing the plurality of images to identify at least one suspicious anomaly appearing in at least two images of the anatomical colon;
- c. by means of at least one processor, based on locations in which the at least one suspicious anomaly appears in the at least two images, creating a display image using a portion of the at least two images, wherein the at least one suspicious anomaly is specially depicted in the display image;
- and
- d. by means of at least one output device, outputting to a user the display image.
A system for identifying suspicious anomalies in an anatomical colon under study, comprising a computer system with at least one processor, at least one storage means and at least one input device, so configured that the system is operable to:
- a. by means of at least one input device, acquire a plurality of images of the anatomical colon;
- b. by means of at least one processor, process the plurality of images to identify at least one suspicious anomaly appearing in at least two images of the anatomical colon;
- c. by means of at least one processor, based on locations in which the at least one suspicious anomaly appears in the at least two images, create a display image using a portion of the at least two images, wherein the at least one suspicious anomaly is specially depicted in the display image;
- and
- d. by means of at least one output device, output to a user the display image.
Dependencies are inferred from the claim text.