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US 2010/0216859 A1Published application
Curcumin analog compositions and related methods
AssigneeCharlesson, LLC
InventorDanyang Chen
Life of this patent
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Abstract
Novel curcumin-analog compounds are disclosed that are antioxidants useful in inhibition of pro-inflammation, angiogenic, and vascular permeability factors and elimination of reactive oxygen species. The curcumin compounds specifically inhibit VEGF and are useful in treating various diseases that are mediated through the oxidative stress pathway, including those that are characterized by inflammation, angiogenesis, or vascular leakage.
Claims13
A composition comprising:
- a compound having the formula:
- and a pharmaceutically acceptable carrier.
A composition comprising:
- a compound having the formula:
- and a pharmaceutically acceptable carrier.
A composition comprising:
- a compound having the formula:
- and a pharmaceutically acceptable carrier.
A method comprising:
- providing an effective amount of an agent having the formula:
- to an animal having a disease.
A method comprising:
- using at least one of the compounds having the formula:
- for the manufacture of a medicament for therapeutic application to a patient having a disease.
Dependencies are inferred from the claim text.