Back to results
US 2010/0215575 A1Published application
Systemic Administration of Chlorotoxin Agents for the Diagnosis and Treatment of Tumors
AssigneeTransmolecular, Inc.
InventorsAlison O'Neill, Douglas B. Jacoby
Life of this patent
Estimating the term…
Abstract
The present invention is directed to methods and compositions for the treatment and diagnosis of neoplastic tumors. The inventive methods generally include systemic (e.g., intravenous) administration of a chloroxotoxin agent that may or may not be labeled.
Claims54
A method of treating an individual with a tumor, the method comprising a step of:
- administering an effective amount of a chlorotoxin agent to the individual, wherein the chlorotoxin agent is administered systemically.
A method of detecting tumor tissue in an individual, the method comprising steps of:
- administering to the individual an effective amount of a labeled chlorotoxin agent, wherein the labeled chlorotoxin agent is administered systemically;
- and
- measuring binding of the labeled chlorotoxin agent to a tissue of interest, wherein an elevated level of binding, relative to normal tissue, indicates that the tissue of interest is tumor tissue.
Dependencies are inferred from the claim text.