Method of predicting potential severity of hepatitis e, probe sets, and primer sets
OwnerKazuaki Takahashi, Natsumi Abe +2inventors
InventorsKazuaki Takahashi, Natsumi Abe, Sheikh Mohammad Fazle Akbar, Michie Hashimoto
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Abstract
The present invention provides a method of predicting potential severity of hepatitis, includes determining that hepatitis in a subject is potentially severe when it is detected that any amino acid is mutated to an amino acid of genotype-4, the any amino acid being amino acid of an amino acid sequence in a region encoded by ORF1 of an HEV genome RNA of genotype 3, and the HEV genome RNA being contained in a specimen nucleic acid taken from the subject infected with genotype-3 HEV.
Claims12
A method of predicting potential severity of hepatitis, comprising:
- determining that hepatitis in a subject is potentially severe when it is detected that any amino acid is mutated to an amino acid of genotype 4, said any amino acid being amino acid of an amino acid sequence in a region encoded by ORF1 of an HEV genome RNA of genotype 3, and said HEV genome RNA being contained in a specimen nucleic acid taken from the subject infected with genotype-3 HEV.
Dependencies are inferred from the claim text.