# US 2010/0168759 A1 · Micro manipulator for electrode movement in neural signal recording

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- Number: US 2010/0168759 A1
- Document ID: US20100168759A1
- Status: Published application
- Kind: A1
- Application number: 12/541,558
- Filed: 2009-08-14
- Published: 2010-07-01
- Earliest claimed: 2008-12-29
- Assignees: Korea Institute of Science and Technology
- Inventors: Eui Sung YOON; Sung Wook Yang; Jin Seok Kim; Duk Moon Rho; Ki Tae Park; Se Min Lee; Jei Won Cho; Hee Sup Shin
- Web page: https://patentgrep.com/patent/US20100168759A1

## CPC

- A61N 1/0529: {Electrodes for brain stimulation}
- A61B 5/0051: {by applying vibrations}
- A61B 5/065: {Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe}
- A61B 5/24: Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B 90/11: with guides for needles or instruments, e.g. arcuate slides or ball joints
- A61B 2017/00398: {using powered actuators, e.g. stepper motors, solenoids}
- A61B 2034/2051: {Electromagnetic tracking systems}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

This disclosure relates to a micro manipulator having a simple structure and having high possibility of recording a biological signal of a neuron at a desired position by improving positioning resolution of an electrode disposed adjacent to a subject's brain neuron or an electrode holder attached with the electrode. The micro manipulator according to the disclosure includes: a motor which includes a shaft and a vibration portion; a mobile which is connected to the shaft so as to be movable along the shaft; and a frame which supports the motor, wherein an electrode is connected to the mobile in a direction parallel to a longitudinal direction of the shaft, and wherein when the mobile moves linearly in accordance with a vibration of the shaft due to the vibration portion, the electrode moves linearly.

## Claims

### Claim 1

A micro manipulator comprising:
a motor which includes a shaft and a vibration portion;
a mobile which is connected to the shaft so as to be movable along the shaft; and
a frame which supports the motor,
wherein an electrode is connected to the mobile in a direction parallel to a longitudinal direction of the shaft, and
wherein when the mobile moves linearly in accordance with a vibration of the shaft due to the vibration portion, the electrode moves linearly.

### Claim 2 (depends on 1)

The micro manipulator according to claim 1,
wherein the vibration portion includes a deforming plate which extends and contracts upon applying a power thereto and an elastic plate which is attached to the deforming plate, and
wherein the shaft is fixed to the deforming plate or the elastic plate and is formed in a direction perpendicular to the elastic plate.

### Claim 3 (depends on 1)

The micro manipulator according to claim 1, further comprising:
an electrode holder which is fixed to the mobile and is formed in a direction parallel to the longitudinal direction of the shaft,
wherein the electrode is mounted to the inside of the electrode holder so as to be connected to the mobile.

### Claim 4 (depends on 3)

The micro manipulator according to claim 3,
wherein the electrode holder is separable from the mobile.

### Claim 5 (depends on 1)

The micro manipulator according to claim 1,
wherein the shaft perforates the center of the frame.

### Claim 6 (depends on 5)

The micro manipulator according to claim 5, further comprising:
a funnel-shaped guide member,
wherein the guide member is coupled to the center of a lower end of the frame so that an end of the electrode extends along an axis of the shaft.

### Claim 7 (depends on 1)

The micro manipulator according to claim 1, further comprising:
a position sensor which measures a displacement of the mobile.

### Claim 8 (depends on 7)

The micro manipulator according to claim 7,
wherein the position sensor includes a permanent magnet and a magnetoresistive sensor, and
wherein the permanent magnet is fixed to the mobile.

### Claim 9 (depends on 1)

The micro manipulator according to claim 1, further comprising:
a control signal transmitting device which receives a control signal generated by a controller so as to operate the motor.

### Claim 10 (depends on 1)

The micro manipulator according to claim 1, further comprising:
a neural signal transmitting device which transmits a signal detected by the electrode to the outside.

### Claim 11 (depends on 7)

The micro manipulator according to claim 7, further comprising:
a position signal transmitting device which transmits displacement information of the mobile measured by the position sensor to the outside.

### Claim 12 (depends on 1)

The micro manipulator according to claim 1, further comprising:
an outer cover which supports the motor, the mobile, and the frame therein in a fixed state.

### Claim 13 (depends on 12)

The micro manipulator according to claim 12,
wherein the outer cover includes an upper cover and a lower cover, and
wherein the upper cover is separable from the lower cover.

### Claim 14 (depends on 1)

The micro manipulator according to claim 1, further comprising:
a plate spring which is coupled to the mobile,
wherein the plate spring is located at a connection portion between the shaft and the mobile so as to apply frictional force between the shaft and the mobile.
