# US 2010/0167930 A1 · Uses of thaxtomin and thaxtomin compositions as herbicides > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2010/0167930 A1 - Document ID: US20100167930A1 - Status: Published application - Kind: A1 - Application number: 12/650,315 - Filed: 2009-12-30 - Published: 2010-07-01 - Earliest claimed: 2008-12-31 - Assignees: Marrone Bio Innovations, Inc. - Inventors: Marja Koivunen; Pamela Marrone - Web page: https://patentgrep.com/patent/US20100167930A1 ## CPC - A01N 43/60: 1,4-Diazines; Hydrogenated 1,4-diazines - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS ## Abstract There is a need for a selective, low-risk herbicide that can be used to control weeds in cereal cultures and turf. The present invention discloses that a bacterial secondary metabolite, thaxtomin and optionally another herbicide is an effective herbicide on broadleaved, sedge and grass weeds. Thaxtomin A and structurally similar compounds can be used as natural herbicides to control the germination and growth of weeds in cereal, turf grass, Timothy grass and pasture grass cultures with no phytotoxicity to these crops. As a natural, non-toxic compound, thaxtomin can be used as a safe alternative for weed control in both conventional and organic farming and gardening systems. ## Claims ### Claim 1 A method for modulating germination and growth of monocotyledonous, dicotyledonous and sedge weeds in a non-rice cereal crop growth system and/or a turf grass growth system and/or Timothy grass growth system and/or pasture grass growth system, comprising applying to said weeds or soil in said growth system at least one herbicidal agent, wherein said herbicidal agent is thaxtomin, in an amount of effective to modulate growth of said weeds but not modulate growth of non-rice cereal crop in said non-rice cereal crop growth system and/or turf, pasture and/or Timothy grass in said turf, pasture and/or Timothy grass growth system. ### Claim 2 (depends on 1) The method according to claim 1, wherein said cereal crop is at least one of wheat, triticale, barley, oats, rye, corn, sorghum, sugarcane or millet. ### Claim 3 (depends on 3) The method according to claim 3, wherein said turf grass is selected from the group consisting of Festuca sp., Poa sp., Bromus sp., Lolium sp., Agrostis sp., Zoysia sp., Cynodon sp. ### Claim 4 (depends on 1) The method according to claims 1, wherein the thaxtomin has the following composition: wherein R1 is methyl or H, R2 is hydroxy or H, R3 is methyl or H, R4 is hydroxy or H, R5 is hydroxy or H, R6 is hydroxy or H, and combinations thereof. ### Claim 5 (depends on 1) The method according to claims 1, wherein the weed is selected from the group consisting of Chenopodium album, Abutilon theophrasti, Helianthus annuus, Ambrosia artemesifolia, Amaranthus retroflexus, Convolvulus arvensis, Brassica kaber, Taraxacum officinale, Solanum nigrum, Malva neglect, Setaria lutescens, Bromus tectorum, Poa annua, Poa pratensis, Lolium perenne L. var. Pace, Festuca arundinaceae Schreb. var. Aztec II, Anthem II, LS1100, Echinochloa crus-galli. ### Claim 6 A method for modulating growth of monocotyledonous, dicotyledonous and sedge weeds and aquatic weeds selected from the group consisting of Ammania sp., Alisma plantago-aquatica, Cyperus sp., Leptochloa sp. comprising applying to said weeds or soil an amount of at least two herbicidal agents effective to modulate growth of said weeds, wherein a first herbicidal agent is thaxtomin. ### Claim 7 (depends on 6) The method according to claim 6, wherein said monocotyledonous, dicotyledonous and sedge weeds are modulated in a cereal growth system. ### Claim 8 (depends on 7) The method according to claim 7, wherein the cereal growth system is a rice growth system. ### Claim 9 (depends on 6) The method according to claim 6, wherein said second herbicidal agent is a chemical herbicide or bioherbicide. ### Claim 10 (depends on 6) The method according to claim 6, wherein the second herbicidal agent is a chemical herbicide selected from the group consisting of diflufenzopyr and salts thereof, dicamba and salts thereof, topramezone, tembotrione, S-metolachlor, atrazine, mesotrione, primisulfuron-methyl, 2,4-dichlorophenoxyacetic acid, nicosulfuron, thifensulfuron-methyl, asulam, metribuzin, diclofop-methyl, fluazifop, fenoxaprop-p-ethyl, asulam, oxyfluorfen, rimsulfuron, mecoprop, and quinclorac, thiobencarb, clomazone, cyhalofop, propanil, bensulfuron-methyl, penoxsulam, triclopyr, imazethapyr, halosulfuron-methyl, pendimethalin, bispyribac-sodium, carfentrazone ethyl, sodium bentazon/sodium acifluorfen, orthosulfamuron. ### Claim 11 (depends on 6) The method according to claim 6, wherein the second herbicidal agent is a bioherbicide selected from the group consisting of clove, cinnamon, lemongrass, citrus oils, orange peel oil, tentoxin, cornexistin, AAL-toxin, leptospermone, sarmentine, momilactone B, sorgoleone, ascaulatoxin and ascaulatoxin aglycone. ### Claim 12 (depends on 6) The method according to claim 6, wherein the first and second herbicidal agents are applied in rotation. ### Claim 13 (depends on 6) The method according to claim 6, wherein the first and second herbicidal agents are applied together. ### Claim 14 An herbicidal composition comprising at least two herbicides wherein a first herbicide is thaxtomin and a second herbicide is a bioherbicide or chemical herbicide. ### Claim 15 (depends on 14) The composition according to claims 14, wherein said composition further comprises an adjuvant, a non-ionic surfactant and/or an organic solvent. ### Claim 16 (depends on 14) The composition according to claims 14, wherein said composition further comprises a non-ionic surfactant and/or an aliphatic alcohol.