Biodegradable osteogenic porous biomedical implant with impermeable membrane
AssigneeWarsaw Orthopedic, Inc.
InventorWilliam F. McKay
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Abstract
A biomedical implant is disclosed with osteogenic factors and a solid impermeable membrane occluding a portion of its surface for the generation of new bone growth at the target site of the implant. The implant is porous, bioresorbable, and forms a three dimensional architectural scaffold for the formation of new bone tissue. The implant is formed with a polymer or collagen, bone morphogenetic protein and ceramic particles.
Claims33
A biomedical implant comprising:
- a porous biodegradable scaffold matrix comprising collagen and a calcium compound comprising calcium chloride;
- and
- an effective amount of a bone morphogenic protein incorporated into the scaffold matrix to cause new bone growth.
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A biomedical implant kit comprising:
- a preformed scaffold matrix comprising collagen;
- an effective amount of bone morphogenic protein, and a calcium compound comprising calcium chloride;
- and
- a re-hydrating solution to incorporate the bone morphogenic protein into the scaffold matrix.
A biomedical implant comprising:
- a porous biodegradable scaffold matrix comprising hyaluronic acid and a calcium compound comprising calcium chloride;
- and
- an effective amount of a bone morphogenic protein incorporated into the scaffold matrix to cause new bone growth.
Dependencies are inferred from the claim text.