Infusion device with impedance measurement cross-reference to related applications

An ambulatory infusion device for the infusion of a liquid drug into a patient's body over an extended time period, comprising:

• a) an infusion cannula designed to be placed in the patient's subcutaneous tissue;
• b) at least two subcutaneous electrodes, the at least two subcutaneous electrodes being comprised by the infusion cannula and being placed in the subcutaneous tissue;
• c) an impedance measuring unit, the impedance measuring unit being operatively coupled to the at least two electrodes and configured to measure at least one impedance value between the at least two electrodes, a variation of the at least one impedance value reflecting a displacement of interstitial fluid by drug upon drug administration;
• d) an event trigger unit operatively coupled to the impedance measuring unit and being configured to evaluate the at least one impedance value and to generate an event trigger if evaluation of the at least one impedance value indicates the occurrence of an administration anomaly.