Therapeutic success prediction for atrial fibrillation

A computer-implemented system for assessing a patient's risk for recurrent atrial fibrillation (AF) following treatment with an AF treatment modality, the system comprising:

• a processing module that determines, from left atrium (LA) tissue image data of a patient, a level of a parameter that is positively proportional or negatively proportional to an amount of unhealthy tissue in a wall of the LA of the patient;
• and
• an output module, in communication with the processing module, that outputs a machine-readable indicator of a comparison between (i) the determined level and (ii) a first threshold level of the parameter, the first threshold level derived from LA tissue image data of at least one other patient, who experienced an AF recurrence after treatment with the AF treatment modality;
• wherein, when the level of the parameter is positively proportional to the amount of unhealthy tissue, levels of the parameter equal to or greater than the first threshold level are indicative of a significant risk of AF recurrence after treatment with the AF treatment modality;
• wherein, when the level of the parameter is negatively proportional to the amount of unhealthy tissue, levels of the parameter equal to less than the first threshold level are indicative of a significant risk of AF recurrence after treatment with the AF treatment modality.