Back to results
US 2010/0160756 A1Published application
Membrane Layer for Electrochemical Biosensor and Method of Accommodating Electromagnetic and Radiofrequency Fields
AssigneeEdwards Lifesciences Corporation
InventorsJames R. Petisce, Henry W. Oviatt
Life of this patent
Estimating the term…
Abstract
A method comprising providing an in vivo electrochemical biosensor, the biosensor comprising an electrode surface, a flux-limiting layer covering at least a portion of the electrode surface, covering at least a portion of the flux-limiting layer with a hydrophilic polymer membrane, and preventing or eliminating disruption of the output signal of the electrochemical biosensor by an external EMF or external RF source during in vivo use of the biosensor in a subject.
Claims25
A method comprising:
- providing an in vivo electrochemical biosensor, the biosensor comprising:
- an electrode surface;
- a flux-limiting layer covering at least a portion of the electrode surface;
- covering at least a portion of the flux-limiting layer with a hydrophilic polymer membrane;
- and
- reducing disruption of the output signal of the electrochemical biosensor by an external EMF or external RF source during in vivo use of the biosensor.
3 more elements
An electrochemical analyte sensor, comprising:
- an in vivo biosensor capable of sensing an analyte level in blood and outputting a signal corresponding to the analyte concentration, the in vivo biosensor comprising:
- an electrode surface;
- an enzyme layer covering at least a portion of the electrode surface;
- a flux-limiting layer covering at least a portion of the enzyme layer and at least a portion of the electrode surface;
- and
- a hydrophilic polymer membrane covering at least a portion of the flux-limiting layer;
- wherein disruption of the output signal of the analyte sensor, when operated in the presence of an external EMF or external RF source during in vivo use is reduced.
4 more elements
A method comprising:
- providing an in vivo electrochemical biosensor, the biosensor comprising:
- an electrode surface;
- a hydrophilic layer covering at least a portion of the electrode surface;
- an interference layer covering at least a part of the hydrophilic layer;
- an enzyme layer covering at least a part of the interference layer;
- a flux-limiting layer covering at least a portion of the enzyme layer;
- covering at least a portion of the flux-limiting layer with a hydrophilic polymer membrane, wherein the hydrophilic polymer membrane comprises a material selected from the group consisting of poly-N-vinylpyrrolidone, polyacrylamide, polyvinyl acetate, and polyelectrolyte;
- and
- reducing disruption of the output signal of the electrochemical biosensor by an electrosurgical unit (ESU) during in vivo use of the biosensor in a subject.
6 more elements
Dependencies are inferred from the claim text.