Process and apparatus for the production of hydroxytyrosol containing extract from olives and solids containing residues of olive oil extraction
AssigneeProbelte Pharma, S.A.
InventorsJose A. Lopez Mas, Sergio A. Streitenberger, Marcos Penalver Mellado, Pedro Martinez Ortiz
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Abstract
Hydroxytyrosol is extracted from olives and/or from the solid residues of olives after the extraction of olive oil, by carrying out acid hydrolysis at a temperature within the range of 110° C. to 140° C. and at a pH within the range of 1.0 to 6.0, and by purifying the obtained solution on a column containing acid activated anion exchange resins, and a column containing an adsorbent non-ionic resin; both columns being eluted with water to recover the hydroxytyrosol.
Claims16
-16. (canceled)
A process of producing an extract containing hydroxytyrosol from a starting material selected from olives and/or pomaces residues of olives after an extraction of olive oil, said process including acid hydrolysis of said starting material and purification of the resulting solution, the process comprising:
- a) carrying out said acid hydrolysis of said starting material in water at a temperature within the range of 70° C. to 140° C., at a pressure within the range of atmospheric pressure to 20 psi above the atmospheric pressure and at a pH within the range of 1.0 to 6.0;
- b) removing suspended solids from the hydrolysis water solution of step a) to obtain a clarified aqueous solution;
- c) loading a product (A) obtained from step b) in a chromatographic column of a resin selected from acid activated anion exchange resins to retain hydroxytyrosol,
- d) eluting the products retained over said chromatographic resin with water;
- e) loading a solution (B) obtained from step d) in a second chromatographic column of a resin selected from adsorbent non-ionic resins, to retain hydroxytyrosol;
- f) eluting the products retained over said second chromatographic resin with water.
An apparatus for producing an extract containing hydroxytyrosol from a starting material selected from olives and/or pomaces residues of olives after an extraction of olive oil, comprising:
- means of acid hydrolysis of said by-product, including means for carrying out said acid hydrolysis at a temperature within the range of 70° C. to 140° C. and at a pH within the range of 1.0 to 6.0;
- and
- means for treating the hydrolysis product to obtain a clarified aqueous solution;
- a chromatographic column of a resin selected from acid activated anion exchange resins and a second chromatographic column of a resin selected from adsorbent non-ionic resins.
Dependencies are inferred from the claim text.