Polymethylmethacrylate bone cement composition for controlled hyperthermia treatment
AssigneeHeraeus Medical GmbH
InventorsSebastian VOGT, Hubert Büchner
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Abstract
The invention relates to a polymethylmethacrylate bone cement composition that contains polymethylmethacrylate, radio-opaquer, methylmethacrylate and/or alkylmethacrylates, and an initiator system and comprises, in addition, ferromagnetic and/or superparamagnetic particles of a particle size of up to maximally 500 μm—which allows it to be heated by alternating magnetic fields—and further contains at least one biodegradable or biocompatible crystalline substance having a melting point in the range of 43-46° C. The cured cement can be used for local over-heating (hyperthermia) therapy in the absence of undesired temperature peaks.
Claims9
A polymethylmethacrylate bone cement composition for controlled hyperthermia treatment comprising,
- A polymethylmethacrylate;
- B radio-opaquer;
- C methylmethacrylate and/or alkylmethacrylates;
- D initiator system;
- E ferromagnetic and/or superparamagnetic particles having a particle size of up to 500 μm;
- and
- F at least one biodegradable or biocompatible crystalline substance having a melting point in the range of 42-80° C.
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Dependencies are inferred from the claim text.