Propofol Solution for Anesthetic Use
OwnerCiriaco Quirogainventor
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Abstract
A transparent anesthetic solution for intravenous injection comprising at least 55% to 90% propofol dissolved in 10% to 45% of Macrogol 15 Hydroxystearate (SOLUTOL® HS 15), preferably having 25% by weight of Macrogol 15 Hydroxystearate (SOLUTOL® HS 15) for each 10.815 mg/ml of propofol. The solution may also include 0.0515 mg/ml of EDTA for each 10.815 mg/ml of propofol. The compositions result in decreased venous irritation and extends the shelf-life.
Claims3
1- PROPOFOL TRANSPARENT ANESTHETIC SOLUTION, WITH LOW VENOUS IRRITATION THRESHOLD characterized by being composed, at least, by 90% to 55% of Propofol, dissolved in 10% to 45% of Macrogol 15 hydroxyestearate (Solutol).
2- PROPOFOL TRANSPARENT ANESTHETIC SOLUTION, WITH LOW VENOUS IRRITATION THRESHOLD in accordance with what has been claimed in 1, characterized by having 25% of Macrogol 15 hydroxyestearate (Solutol) for each 10.815 mg/ml of Propofol.
3- PROPOFOL TRANSPARENT ANESTHETIC SOLUTION, WITH LOW VENOUS IRRITATION THRESHOLD in accordance what has been claimed in 1 and 2, characterized by having 0.0515 mg/ml of EDTA for each 10.815 mg/ml of Propofol.