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US 2010/0160433 A1Published application
Treatment of neurodegenerative and cardiovascular disorders
AssigneeYangsheng Du
InventorsYansheng Du, Martin R. Farlow, Ruyu Du
Life of this patent
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Abstract
A method of treating a neurodegenerative or cardiovascular disorder with a compound of the following formula: in which X, Y, A1, A2, R1, and R2 are defined herein.
Claims22
1-21. (canceled)
A method of treating Parkinson's disease, heart failure, or cardiomyopathy, comprising administering to a subject in need thereof an effective amount of a compound of the following formula:
- in which
- each of R1 and R2, independently, is C1-8 alkylene, C2-8 alkenylene, or deleted;
- each of A1 and A2, independently, is aryl or heteroaryl, optionally substituted with halogen, —CN, —NO2, —OH, —SH, —OR3, —SR3, —R3, —R3—OR4, —C(O)R3, —S(O)R3, —S(O)2R3, —NR4R5, —C(O)OR3, —C(O)NR4R5, —O(O)CR4, or —NR4(O)CR5;
- and
- each of X and Y, independently, is O, S, or NR6;
- wherein each R3 is C1-4 alkyl, and each of R4, R5, and R6, independently, is H or C1-4 alkyl.
3 more elements
Dependencies are inferred from the claim text.